Pancreatic cancer is one of the most
fatal cancers around the world, with the highest incidence and mortality rates
found in developed countries (Michaud, 2004). Pancreatic cancer originates from
transformed cells from tissues within the exocrine component of the pancreas.
The most common type is adenocarcinoma associated with the exocrine gland (ACS,
2013). The pancreas is found deep within the body, leading to the inability to
detect pancreatic cancer early-on. Most cases of pancreatic cancer go
undetected from the lack of obvious symptoms, causing the cancer to spread to
other organs.
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The risk of developing pancreatic
cancer is associated with increasing age, as more than 75% of pancreatic cancer
patients are over the age of 60 years (SEER Cancer Statistics Review, 2012).
Tobacco smoking is one of the most common risk factors for pancreatic cancer,
as smokers have a two-fold increased risk of developing the disease compared
with nonsmokers (Lowenfels and Maisonneuve, 2006). Due to the short survival
period and high mortality for pancreatic cancer, patients with the disease are
less likely to suffer from comorbidities than patients with other types of
cancer.
GlobalData forecasts that the US and
Germany will have the highest number of incident cases of pancreatic cancer in
2022. GlobalData epidemiologists also expect that the number of prevalent cases
of pancreatic cancer in the 6MM covered will increase during the forecast
period (2012–2022) to a total of 59,675 cases. The stage at diagnosis for
pancreatic cancer is correlated with the availability of screening tests and
the ability to identify early symptoms. Due to the inability to identify early
indications of the illness, pancreatic cancer cases are most commonly diagnosed
in Stage IV. Greater research in prevention and early diagnostic testing can
help reduce the incidence of the disease. Through early detection, it may be
possible to stop the spread of the cancer to other organs and decrease the
overall mortality.
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