Autacoids are certain biological
factors that act like hormones and help in treating local injuries and other
ailments. Autacoids are temporarily formed in the body and act locally. They
have many different actions such as modulation of action of glands, smooth
muscles, platelets, nerves, and other tissues. They are released by stimuli and
when they are released into the body, they can bring certain changes such as
itching, skin reddening, and bronchospasms. Some of these changes are
undesirable and for the prevention of such symptoms, autacoids antagonists are
used.
Autacoids are classified into
decarboxylated amino acids, polypeptides, and eicosanoids. The major forms of
decarboxylated amino acids are histamine and serotonin. The major polypeptides
in autacoids are angiotensin, vasopressin, plasma kinin, substance P,
vasoactive intestinal polypeptide, and slow reacting substances of anaphylaxis.
It has been recently discovered that some autacoids such as histamine,
serotonin, and prostaglandin are found in nerve tissues. The major functional
applications of autacoids are in treating inflammation, allergies,
neurotransmission, anaphylactic reactions, gastric acid secretion, and
neuroendocrine regulation.
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It is estimated that the global
market for autacoids and related drugs will cross the 100 billion mark by 2018.
The major drugs related to autacoids are biogenic amines, polypeptide
autacoids, drugs related to lipid-derived autacoids, and drugs related to
endothelium derived autacoids. The dominant segment in the autacoids market is
biogenic amines. This segment captures more than 65% of the overall autacoids
market. The major application segment of the market are the use of
autacoids related drugs in respiratory and cardiovascular diseases, CNS
diseases, antiemetics, gastrointestinal diseases, eye disorders, and
analgesics.
Some of the major market players in
the autacoids and autacoids related drugs market are Abbott Laboratories, APP
Pharma, AstraZeneca, Bedford Laboratories, Bristol-Myers Squibb, Chattem Inc.,
Hospira Inc., Sanofi-Aventis, Xanodyne, and some others.
This research report analyzes this
market depending on its market segments, major geographies, and current market
trends. Geographies analyzed under this research report include
- North America
- Asia Pacific
- Europe
- Rest of the World
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