Research Report On Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth Description
Research has released its pharma report “Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth”. The systemic psoriasis market is forecast to grow substantially over the forecast period from $5.0 billion in 2013 to $10.4 billion in 2020, across the eight major markets. This growth will be driven by a rising treatment population and the continued uptake of biologics. Biologics will continue to drive market growth despite leading brands Enbrel (etanercept), Humira (adalimumab) and Remicade (infliximab) losing patent protection in most of the major markets over the forecast period. Although the market will suffer revenue losses as a result of sales erosion from biosimilar competitors, this will be offset by the emergence of novel therapies. Most notably, these include monoclonal antibodies secukinumab, ixekizumab and brodalumab, which are currently being developed by Alcon (Novartis subsidiary), Eli Lilly and Amgen, respectively.
To Read Complete Report with TOC: http://www.marketresearchreports.biz/analysis-details/systemic-psoriasis-therapeutics-in-major-developed-markets-to-2020-continued-uptake-of-biologics-and-novel-pipeline-drugs-to-drive-growth-description
Scope
• An introduction to psoriasis, which includes symptoms, epidemiology, etiology, pathophysiology, diagnosis and treatment
• Analysis of the major systemic therapies in the current psoriasis marketed landscape
• Analysis of the pipeline for psoriasis, which includes a breakdown of pipeline molecules by phase of development, molecule type, molecular target and novelty. Psoriasis clinical trials are analyzed by size, duration and failure rates, and a comparative analysis of the most promising systemic pipeline molecules is also provided.
• Forecast projections for the systemic psoriasis market to 2020. Analysis is provided for the global market and each of the eight major markets. The forecast incorporates projected, low and high variance scenarios based on treatment usage patterns and annual therapy costs in each of the major markets.
• Analysis of strategic consolidations, including co-development and licensing deals, within the psoriasis indication
Reasons to Buy
• Understand the current systemic psoriasis marketed products landscape and recognize the dominant therapeutic agents and pharmaceutical players involved
• Identify trends and developments within the psoriasis pipeline and consider how the future competitive environment will be impacted
• Consider market opportunities and potential risks by examining the psoriasis clinical trial landscape in relation to industry averages
• Observe projections for treatment usage patterns, annual therapy costs and market growth in the eight major markets and understand reasons for variance in projected patterns of growth in the eight major markets
To Get Download Full Report with TOC: http://www.marketresearchreports.biz/sample/sample/186872
Table of Content
1 Table of Contents 1
1.1 List of Tables 4
1.2 List of Figures 5
2 Executive Summary 6
2.1 Changes to Treatment Usage Patterns will Drive Market Growth 6
2.2 Biologics to Gain Prominence as Promising Novel Drugs Enter the Market 6
3 Introduction 7
3.1 Overview 7
3.2 Epidemiology 8
3.3 Etiology, Co-morbidities and Risk Factors 9
3.3.1 Genetics 9
3.3.2 Psoriatic Arthritis 9
3.3.3 Mental Health Disorders 10
3.3.4 Metabolic Syndrome, Smoking, Diet and Alcohol Consumption 10
3.3.5 Infections 10
3.3.6 Köebner Phenomenon 11
3.3.7 Other Immune-mediated Diseases 11
3.4 Pathophysiology 11
3.5 Diagnosis 12
3.6 Treatment Options 12
3.6.1 Pharmacological Therapies 13
3.6.2 Non-pharmacological Therapies 14
3.6.3 Combination and Rotational Therapies 14
3.6.4 Quality of Life Assessments 15
3.7 Summary 15
3.8 GBI Research Report Guidance 15
4 Marketed Products 16
4.1 Overview 16
4.2 Methotrexate-based Products 16
4.3 Sandimmune/Neoral (cyclosporine/modified cyclosporine) – Novartis 17
4.4 Soriatane (acitretin) – Steifel Laboratories 18
4.5 Fumaderm (dimethyl fumarate and ethyl fumarate) – Biogen Idec 19
4.6 Humira (adalimumab) – Abbvie Inc. 20
4.7 Enbrel (etanercept) – Amgen Inc. 21
4.8 Remicade (infliximab) – Janssen Biotech 22
4.9 Stelara (ustekinumab) – Janssen Biotech 23
4.10 Marketed Products Heat Map 24
To Buy The Copy of This Report Visit: http://www.marketresearchreports.biz/analysis/186872
5 Pipeline 27
5.1 Overview 27
5.2 Pipeline Size and Distribution by Phase, Molecule Type and Program Type 28
5.3 Pipeline Distribution by Molecular Target 30
5.4 Clinical Trial Landscape 32
5.4.1 Clinical Trial Duration 32
5.4.2 Clinical Trial Size 36
5.5 Clinical trial failure rates 40
5.6 Primary and Secondary Endpoints 41
5.7 Summary of Psoriasis Clinical Trials 43
5.8 Promising pipeline molecules 43
5.8.1 Ixekizumab – Eli Lilly 43
5.8.2 Xeljanz (tofacitinib) – Pfizer 44
5.8.3 Brodalumab – Amgen 45
5.8.4 Apremilast – Celgene 46
5.8.5 Secukinumab – Alcon 47
5.9 Heat Map for Pipeline Products 47
6 Market Forecast to 2020 52
6.1 Overview 52
6.2 Global Market 52
6.3 North America 55
6.3.1 Treatment Usage Patterns 55
6.3.2 Annual Cost of Treatment 56
6.3.3 Market Size 58
6.4 Top Five EU Markets 59
6.4.1 Treatment Usage Patterns 59
6.4.2 Annual Cost of Treatment 60
6.4.3 Market Size 61
6.5 Japan 62
6.5.1 Treatment Usage Patterns 62
6.5.2 Annual Cost of Treatment 63
6.5.3 Market Size 64
6.6 Drivers and Barriers for the Systemic Psoriasis Therapeutics Market 65
6.6.1 Drivers 65
6.6.2 Barriers 65
7 Co-development and Licensing deals 67
7.1 Co-development Deals 67
7.1.1 Abbvie Enters into Co-development Agreement with Biotest for Tregalizumab 70
7.1.2 Lycera Enters into Research Agreement with Merck & Co. 70
7.1.3 LEO Pharma Enters into Research Agreement with 4SC Discovery for Inflammatory Skin Diseases 70
7.1.4 Amgen Enters into Co-Development Agreement with AstraZeneca for Five Human Monoclonal Antibodies Including Brodalumab 70
7.2 Licensing Deals 72
7.2.1 Leo Pharma Enters into Licensing Agreement with Virobay for Psoriasis Drug 75
7.2.2 Foamix Enters into Licensing Agreement with Dr. Reddy\'s Labs 75
7.2.3 Cipher Pharma Enters into Licensing Agreement with IBSA Institut Biochimique for Betesil Patch 75
7.2.4 Phenex Pharma Enters into Licensing Agreement with Janssen Biotech for Retinoid-Acid Receptor-Related Orphan Receptor Gamma t Program 75
8 Appendix 76
About us
MarketResearchReports.biz is the most comprehensive collection of market research reports. MarketResearchReports.Biz services are specially designed to save time and money for our clients. We are a one stop solution for all your research needs, our main offerings are syndicated research reports, custom research, subscription access and consulting services. We serve all sizes and types of companies spanning across various industries.
Contact
M/s Sheela
90 Sate Street, Suite 700
Albany, NY 12207
Tel: +1-518-618-1030
USA – Canada Toll Free: 866-997-4948
Blog: http://mrrfocuseconomics.blogspot.com/
Research has released its pharma report “Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth”. The systemic psoriasis market is forecast to grow substantially over the forecast period from $5.0 billion in 2013 to $10.4 billion in 2020, across the eight major markets. This growth will be driven by a rising treatment population and the continued uptake of biologics. Biologics will continue to drive market growth despite leading brands Enbrel (etanercept), Humira (adalimumab) and Remicade (infliximab) losing patent protection in most of the major markets over the forecast period. Although the market will suffer revenue losses as a result of sales erosion from biosimilar competitors, this will be offset by the emergence of novel therapies. Most notably, these include monoclonal antibodies secukinumab, ixekizumab and brodalumab, which are currently being developed by Alcon (Novartis subsidiary), Eli Lilly and Amgen, respectively.
To Read Complete Report with TOC: http://www.marketresearchreports.biz/analysis-details/systemic-psoriasis-therapeutics-in-major-developed-markets-to-2020-continued-uptake-of-biologics-and-novel-pipeline-drugs-to-drive-growth-description
Scope
• An introduction to psoriasis, which includes symptoms, epidemiology, etiology, pathophysiology, diagnosis and treatment
• Analysis of the major systemic therapies in the current psoriasis marketed landscape
• Analysis of the pipeline for psoriasis, which includes a breakdown of pipeline molecules by phase of development, molecule type, molecular target and novelty. Psoriasis clinical trials are analyzed by size, duration and failure rates, and a comparative analysis of the most promising systemic pipeline molecules is also provided.
• Forecast projections for the systemic psoriasis market to 2020. Analysis is provided for the global market and each of the eight major markets. The forecast incorporates projected, low and high variance scenarios based on treatment usage patterns and annual therapy costs in each of the major markets.
• Analysis of strategic consolidations, including co-development and licensing deals, within the psoriasis indication
Reasons to Buy
• Understand the current systemic psoriasis marketed products landscape and recognize the dominant therapeutic agents and pharmaceutical players involved
• Identify trends and developments within the psoriasis pipeline and consider how the future competitive environment will be impacted
• Consider market opportunities and potential risks by examining the psoriasis clinical trial landscape in relation to industry averages
• Observe projections for treatment usage patterns, annual therapy costs and market growth in the eight major markets and understand reasons for variance in projected patterns of growth in the eight major markets
To Get Download Full Report with TOC: http://www.marketresearchreports.biz/sample/sample/186872
Table of Content
1 Table of Contents 1
1.1 List of Tables 4
1.2 List of Figures 5
2 Executive Summary 6
2.1 Changes to Treatment Usage Patterns will Drive Market Growth 6
2.2 Biologics to Gain Prominence as Promising Novel Drugs Enter the Market 6
3 Introduction 7
3.1 Overview 7
3.2 Epidemiology 8
3.3 Etiology, Co-morbidities and Risk Factors 9
3.3.1 Genetics 9
3.3.2 Psoriatic Arthritis 9
3.3.3 Mental Health Disorders 10
3.3.4 Metabolic Syndrome, Smoking, Diet and Alcohol Consumption 10
3.3.5 Infections 10
3.3.6 Köebner Phenomenon 11
3.3.7 Other Immune-mediated Diseases 11
3.4 Pathophysiology 11
3.5 Diagnosis 12
3.6 Treatment Options 12
3.6.1 Pharmacological Therapies 13
3.6.2 Non-pharmacological Therapies 14
3.6.3 Combination and Rotational Therapies 14
3.6.4 Quality of Life Assessments 15
3.7 Summary 15
3.8 GBI Research Report Guidance 15
4 Marketed Products 16
4.1 Overview 16
4.2 Methotrexate-based Products 16
4.3 Sandimmune/Neoral (cyclosporine/modified cyclosporine) – Novartis 17
4.4 Soriatane (acitretin) – Steifel Laboratories 18
4.5 Fumaderm (dimethyl fumarate and ethyl fumarate) – Biogen Idec 19
4.6 Humira (adalimumab) – Abbvie Inc. 20
4.7 Enbrel (etanercept) – Amgen Inc. 21
4.8 Remicade (infliximab) – Janssen Biotech 22
4.9 Stelara (ustekinumab) – Janssen Biotech 23
4.10 Marketed Products Heat Map 24
To Buy The Copy of This Report Visit: http://www.marketresearchreports.biz/analysis/186872
5 Pipeline 27
5.1 Overview 27
5.2 Pipeline Size and Distribution by Phase, Molecule Type and Program Type 28
5.3 Pipeline Distribution by Molecular Target 30
5.4 Clinical Trial Landscape 32
5.4.1 Clinical Trial Duration 32
5.4.2 Clinical Trial Size 36
5.5 Clinical trial failure rates 40
5.6 Primary and Secondary Endpoints 41
5.7 Summary of Psoriasis Clinical Trials 43
5.8 Promising pipeline molecules 43
5.8.1 Ixekizumab – Eli Lilly 43
5.8.2 Xeljanz (tofacitinib) – Pfizer 44
5.8.3 Brodalumab – Amgen 45
5.8.4 Apremilast – Celgene 46
5.8.5 Secukinumab – Alcon 47
5.9 Heat Map for Pipeline Products 47
6 Market Forecast to 2020 52
6.1 Overview 52
6.2 Global Market 52
6.3 North America 55
6.3.1 Treatment Usage Patterns 55
6.3.2 Annual Cost of Treatment 56
6.3.3 Market Size 58
6.4 Top Five EU Markets 59
6.4.1 Treatment Usage Patterns 59
6.4.2 Annual Cost of Treatment 60
6.4.3 Market Size 61
6.5 Japan 62
6.5.1 Treatment Usage Patterns 62
6.5.2 Annual Cost of Treatment 63
6.5.3 Market Size 64
6.6 Drivers and Barriers for the Systemic Psoriasis Therapeutics Market 65
6.6.1 Drivers 65
6.6.2 Barriers 65
7 Co-development and Licensing deals 67
7.1 Co-development Deals 67
7.1.1 Abbvie Enters into Co-development Agreement with Biotest for Tregalizumab 70
7.1.2 Lycera Enters into Research Agreement with Merck & Co. 70
7.1.3 LEO Pharma Enters into Research Agreement with 4SC Discovery for Inflammatory Skin Diseases 70
7.1.4 Amgen Enters into Co-Development Agreement with AstraZeneca for Five Human Monoclonal Antibodies Including Brodalumab 70
7.2 Licensing Deals 72
7.2.1 Leo Pharma Enters into Licensing Agreement with Virobay for Psoriasis Drug 75
7.2.2 Foamix Enters into Licensing Agreement with Dr. Reddy\'s Labs 75
7.2.3 Cipher Pharma Enters into Licensing Agreement with IBSA Institut Biochimique for Betesil Patch 75
7.2.4 Phenex Pharma Enters into Licensing Agreement with Janssen Biotech for Retinoid-Acid Receptor-Related Orphan Receptor Gamma t Program 75
8 Appendix 76
About us
MarketResearchReports.biz is the most comprehensive collection of market research reports. MarketResearchReports.Biz services are specially designed to save time and money for our clients. We are a one stop solution for all your research needs, our main offerings are syndicated research reports, custom research, subscription access and consulting services. We serve all sizes and types of companies spanning across various industries.
Contact
M/s Sheela
90 Sate Street, Suite 700
Albany, NY 12207
Tel: +1-518-618-1030
USA – Canada Toll Free: 866-997-4948
Blog: http://mrrfocuseconomics.blogspot.com/
